Manati has a doctor of pharmacy and master of science in food, nutrition, and dietetics, and has worked at the decision-making and leadership level in different organizations in Afghanistan. She was director of the public nutrition directorate at the Ministry of Public Health in Afghanistan, and previously served as director of the specialists’ directorate at Afghan Atomic Energy High Commission for five years, coordinating all nutrition programs and activities with national and international partners. Manati was an essential author of the development, revision, and strategy of numerous policies concerning health and nutrition, and nuclear and radiological materials waste-management guidelines in Afghanistan. She taught one-year diploma courses in nutrition at Kabul University of Medical Sciences at Ghazanfer Institute of Health Sciences, and organized training programs for a variety of government and non-government agencies.